Publications (5 years):
Journal Articles
2020
Chonge S, Yilong L, Rayat G, Jianbo X, Huamin J, Xian Li, Kunsong Chen. (2020) Trends in Food Science and Technology; Anti-diabetic effects of natural antioxidants from fruits. TIFS-D-20-00118R1. 04/272020 (IF=11.1)
2019
Pecic S, Milosavic N, Rayat G, Maffei A, Harris P. (2019). A Novel Optical Tracer for VMAT2 Applied to Live Cell Measurements of Vesicle Maturation in Cultured Human β Cells. Scientific Reports. 9(1): 5403 (IF=4.3).
Korner J, Cline GW, Slifstein M, Barba P, Rayat GR, (2019) Febres G, Leibel RL, Maffei A, Harris P. A Role of Foregut Tyrosine Metabolism in Glucose Tolerance. Molecular Metabolism. 23: 23-37 (IF=6.3).
Mok D*, Black M*, Gupta N*, Arefanian A*, Tredget E*, Rayat GR. (2019). Early Immune Mechanisms of Neonatal Porcine Islet Xenograft Rejection. Xenotransplantation. Aug 13:e12546: 1-10 (IF=4.7).
2018
Bhavanam S, Rayat GR, (2018) Keelan M, Kunimoto D, Drews SJ. Characterization of immune responses of human PBMCs infected with Mycobacterium tuberculosis H37Ra: Impact of donor declared BCG vaccination history on immune responses and M. tuberculosis growth. PLoS One. 2018;13(9):e0203822. Published 2018 Sep 11. doi:10.1371/journal.pone.0203822
2017
Li C, Yang B, Xu Z, Boivin E*, Black M*, Huang W*, Xu B, Wu P, Zhang B, Li X, Chen K, Wu Y, Rayat GR. (2017) Protective effect of cyanidin-3-O-glucoside on neonatal porcine islets. J Endocrinol. 2017;235(3):237-249. doi:10.1530/JOE-17-0141
Pawlick R, Gala-Lopez B, Pepper AR, Rayat GR (2017) et al. Low energy X-ray (grenz ray) treatment of purified islets prior to allotransplant markedly decreases passenger leukocyte populations. Islets. 2017;9(4):e1330742. doi:10.1080/19382014.2017.1330742
Pawlick R, Gala-Lopez B, Pepper AR, Abualhassan N, Bruni A, Suzuki K, Rayat G, (2017) Elliott JF, Shapiro AMJ. Low energy X-ray (granz ray) treatment of purified islets prior to allotransplant markedly decrease passenger leukocyte populations. Plos One. 9(4): e1330742 (IF=2.8).
2016
Bhavanam S, Rayat GR,(2016) Keelan M, Kunimoto D, Drews SJ. Understanding the pathophysiology of the human TB lung granuloma using in vitro granuloma models. Future Microbiol. 2016;11:1073-1089. doi:10.2217/fmb-2016-0005
Hering BJ, Cozzi E, Spizzo T, Rayat GR (2016) et al. First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes--Executive summary. Xenotransplantation. 2016;23(1):3-13. doi:10.1111/xen.12231
Rayat GR, (2016) Gazda LS, Hawthorne WJ, et al. First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes--Chapter 3: Porcine islet product manufacturing and release testing criteria. Xenotransplantation ; 2016 23(1):38-45. doi:10.1111/xen.12225
Cozzi E, Tönjes RR, Gianello P, Buhler LH, Rayat GR, (2016) Matsumoto S, Park CG, Kwon I, Wang W, O'Connell P, Jessamine S, Elliott RB, Kobayashi T, Hering BJ. First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes--Chapter 1: update on national regulatory frameworks pertinent to clinical islet xenotransplantation. Xenotransplantation; 2016 23(1):14-24. doi:10.1111/xen.12222
Hering BJ, Cozzi E, Spizzo T, Cowan PJ, Rayat GR (2016), Cooper DK, Denner J. First Update of the International Xenotransplantation Association Consensus Statement on Conditions for Undertaking Clinical Trials of Porcine Islet Products in Type 1 Diabetes - Executive Summary. Xenotransplantation. 2016 23(1): 3-13 (IF=3.8).
Bhavanam S*, Rayat GR, (2016) Keelan M, Kunimoto D, Drews SJ. Understanding the Pathophysiology of the Human TB Lung Granuloma Using In Vitro Granuloma Models. Future Microbiol. 2016 11: 1073-89 (IF=3.6).
2015
Arefanian H, Tredget EB, Mok DC, Ramji Q*, Rafati S*, Rodriguez-Barbosa JI, Korbutt GS, Rajotte RV, Gill R, Rayat GR (2015). Porcine Islet-Specific Tolerance Induced by the Combination of Anti-LFA-1 and Anti-CD154 mAbs Is Dependent on PD-1. Cell Transplant.2015;25(2):327-342. doi:10.3727/096368915X688506
Nagaraju S, Bertera S, Tanaka T, Hara H, Rayat GR, (2015) Wijkstrom M, Ayares D, Trucco M, Cooper DK, Bottino R. In Vitro Exposure of Pig Neonatal Islet Like Cell Clusters to Human Blood. Xenotransplantation. 2015; 22(4): 317-324 (IF=3.8).
Wang X, Gupta J, Kerslaki M, Rayat G, (2015) Proctor S, Chan C. Trans-11 Vaccenic Acid Improves Insulin Secretion in Models of Type 2 Diabetes In Vivo and In Vitro. Molecular Nutrition and Food Research. 2015; 60: 846-857 (IF=4.6).
Book Chapters
2017
Croden J*, Huang W*, Rayat GR. (2017) Immune Response Associated with Islet Xenotransplantation in
Small and Large Animal Models. Miyagawa S. Xenotransplantation - New Insights. 1(1): 49-65.
Published, Intech, United Kingdom
Research Funding (5 years):
2020/7 - 2021/9
Co-applicant
In vitro model as a tool to evaluate the effect of chemotherapy and immunotherapy on gastric cancer
Funding Source:
Edmonton Civic Employees Charitable Assistance Fund
Total Funding - 15,000
Funding Competitive?: Yes
Co-applicant: Daniel Skubleny
Principal Applicant : Daniel Schiller
2020/6 - 2022/7
Principal Applicant
C3G-rich extract from Chinese bayberry improves the viability and function of human islets
Funding Source:
China Institute
Total Funding - 5,000
Funding Competitive?: Yes
2017/4 - 2023/3
Principal Applicant
Understanding the Molecular Mechanisms of Early Postnatal Development of Pig Islets
Funding Source:
Natural Sciences and Engineering Research Council of Canada (NSERC)
Discovery Grant
Total Funding - 125,000
Funding Competitive?: Yes
2017/3 - 2021/6
Collaborator
Studies on Novel Anti-Tuberculosis Agents
Funding Source:
Canadian Institutes of Health Research (CIHR)
Project Grant
Total Funding - 668,940
Funding Competitive?: Yes
Principal Applicant: Dennis Kunimoto
2018/4 - 2021/3
Collaborator
The Amylin Receptor: A Potential Therapeutic Target for Alzheimer’s Disease
Funding Source:
Canadian Institutes of Health Research (CIHR)
Project Grant
Total Funding - 739,500
Funding Competitive?: Yes
Collaborator : David Westaway;
Principal Applicant : Jack Jhamandas
2016/10 - 2018/10
Principal Applicant
Evaluation of the Efficacy of CURUS in Preventing Onset of Type 1 Diabetes and Improving Health of Type 1 Diabetic Mice
Funding Source:
GC Marketing Inc.
Research contract
Total Funding - 300,544
Funding Competitive?: No
2017/11 - 2018/10
Principal Applicant
Evaluation of the Effect of CURUS on Mycobacterium tuberculosis Organism Using a Novel In Vitro Granuloma Model
Funding Source:
GC Marketing Inc.
Research contract
Total Funding - 120,000
Funding Competitive?: No
2017/7 - 2018/9
Co-applicant
Expression of Biomarkers in Gastric Cancer and the Effect of Neoadjuvant Chemotherapy
Funding Source:
Edmonton Civic Employees Charitable Assistance Fund
Pilot Grant
Total Funding - 10,000
Funding Competitive?: Yes
Principal Applicant : Daniel Schiller
2012/3 - 2018/2
Co-applicant
Translational Strategies for the Clinical Transplantation of Neonatal Porcine Islets
Funding Source:
Canadian Institutes of Health Research (CIHR)
Operating Grant
Total Funding - 804,467
Funding Competitive?: Yes
Co-applicant : Ray V. Rajotte
Principal Applicant : Gregory S. Korbutt
2015/8 - 2017/1
Principal Applicant
Can Cyanidin-3-O-Glucoside enhance the function and survival of human islets?
Funding Source:
Alberta Diabetes Research Institute
Pilot Research Grant
Total Funding - 30,000
Funding Competitive?: Yes
Co-applicant : Jack Jhamandas
2012/10 - 2014/9
Co-applicant
Effect of Naturally-Occurring Trans Fats on Insulin-Secreting Cells
Funding Source:
Dairy Farmers of Canada
Operating Grant
Total Funding - 76,000
Funding Competitive?: Yes
Principal Applicant : Catherine Chan